Cartilage and endochondral bone development require SOX9 activity to regulate chondrogenesis, chondrocyte proliferation, and transition to a non-mitotic hypertrophic state.The restricted and reciprocal expression of the collagen X gene, Col10a1, in hypertrophic chondrocytes and Sox9 in immature chondrocytes epitomise the precise spatiotemporal cont

Allah Haafiz1, Jonathan L Williams2, Joel M Andres1, Don A Novak11Pediatric Gastroenterology, Hepatology; 2Department of Pediatric Radiology, University of Florida College of Medicine, Gainesville, FL, USAAbstract: A 6-day-old, known to have transposition of Moisturizing milk the great vessels, received care in the neonatal intensive care unit at a

Chronic wasting disease (CWD) is a disease affecting cervids and is caused by prions accumulating as pathogenic fibrils in lymphoid tissue and the central nervous system.Approaches for detecting CWD prions historically relied on antibody-based assays.However, recent advancements in protein amplification technology provided the foundation for a new

Abstract A chronic low-grade inflammation within adipose tissue (AT) seems to be the link between obesity and some of its associated diseases.One Supplies hallmark of this AT inflammation is the accumulation of AT macrophages (ATMs) around dead or dying adipocytes, forming so-called crown-like structures (CLS).To investigate the dynamics of CLS and

Introduction: Migrant workers support low- and middle-income economies through remittances, often bearing considerable health risks with long-term consequences.This study aims to understand the health and wellbeing issues of Nepalese migrant workers in Gulf Cooperation Council (GCC) countries, a major destination for low-skilled Nepalese workers.Me